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PKA phosphorylates Myosin Binding Protein-C (MyBP-C) and troponin I (TnI) within the cardiac myofibril. TnI may be the inhibitory element of the trimeric troponin molecule which makes up the Ca2+-switch of the contractile equipment. TnI binds to TnC when Ca2+ is bound to TnC, even though in the absence of Ca2+, the C-terminus of TnI is released and

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